Clinicopathological characteristics of thrombospondin type 1 domain-containing 7A-associated membranous nephropathy
نویسندگان
چکیده
منابع مشابه
Prevalence of Enhanced Granular Expression of Thrombospondin Type-1 Domain-Containing 7A in the Glomeruli of Japanese Patients with Idiopathic Membranous Nephropathy
Membranous nephropathy (MN) is a leading cause of nephrotic syndrome in adults. Autoantibodies against M-type phospholipase A2 receptor (PLA2R) and thrombospondin type-1 domain-containing 7A (THSD7A), which mainly belong to the IgG4 subclass, were reported as associated antibodies for the development of MN. Although PLA2R is a major target antigen for idiopathic MN, the prevalence of MN patient...
متن کاملHypoxia-inducible miR-210 contributes to preeclampsia via targeting thrombospondin type I domain containing 7A
Preeclampsia, a relatively common pregnancy disorder, is a major contributor to maternal mortality and morbidity worldwide. An elevation in microRNA-210 (miR-210) expression in the placenta has been reported to be associated with preeclampsia. Our bioinformatic analysis showed that thrombospondin type I domain containing 7A (THSD7A) is a predicted target for miR-210. The aim of this study was t...
متن کاملMembranous Nephropathy Associated with Atheroembolism
Membranous nephropathy (MN) is one of the most common biopsy diagnoses in adults, and it has been associated with chronic infections, autoimmune diseases, malignancies, and drugs. However, MN associated with cholesterol crystal emboli has never been reported. Here we present a patient with MN as an unusual manifestation of atheroembolism. A 75-year-old man with worsening renal function after ca...
متن کاملThe clinicopathological features of patients with membranous nephropathy
Background Membranous nephropathy (MN) represents a distinct glomerular disease which has been considered as a major cause of nephrotic syndrome (NS) in adults. Evidences show that the clinicopathological features of MN are various among MN cases. This study aimed to summarize and analyze the clinicopathological features of patients with MN. Methods A total of 231 MN patients were recruited i...
متن کاملMembranous Nephropathy Associated with Tuberculosis
Correspondence To the Editor: Glomerulonephritis (GN) due to Mycobacterium tuberculosis (M. tuberculosis) is rare, [1] and membranous nephropathy (MN) associated with tuberculosis is seldom reported. Because of atypical and nonspecific manifestations, tuberculosis‑associated GN (TB‑GN) is difficult to diagnose. Patients usually present with hematuria, proteinuria, edema, and varying degrees of ...
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ژورنال
عنوان ژورنال: Virchows Archiv
سال: 2019
ISSN: 0945-6317,1432-2307
DOI: 10.1007/s00428-019-02558-0